I will be reloading for the 375 Ruger soon as it's such a versatile cartridge. I just started reloading for the 7mm STW and 243 WSSM but will shift my focus to the 375 Ruger. I must confess... I just bought another rifle! Another Mossberg Patriot in 338 Win Mag. I just couldn't pass it up for under $300 new and shipped!!! Need was not a factor here as one does not really need a 338 owning a 375. But the 338 is another great cartridge I've had success with and I just had to try it in the Patriot with 22 inch barrel. I read a 22 inch tube is good on a 338 mag. Really, a guy/gal/family into rifles/hunting/shooting for fun, buying a Patriot rifle in every caliber is realistically affordable! This year I'll be shooting and hunting with my Patriots a lot and fully expect them to exceed expectations. Most likely the 375 will become my favorite and go to rifle. I can just envision using it to hunt Alaskan/Yukon moose with it! I will try the iron sights on the 375 Patriot and used to think iron sights as back up were a good idea. Yet I've never actually hunted with iron sights, especially since scopes are so reliable these days and may remove the iron sights from my Patriot? Otherwise I'll be tempted to mount my scope with QR rings.